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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRB10
All Species:
6.36
Human Site:
S104
Identified Species:
15.56
UniProt:
Q13322
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13322
NP_001001549.1
594
67231
S104
R
S
I
Q
P
Q
V
S
P
R
Q
R
V
Q
R
Chimpanzee
Pan troglodytes
XP_001154916
594
67198
S104
R
S
V
Q
P
Q
V
S
P
R
Q
R
V
Q
R
Rhesus Macaque
Macaca mulatta
XP_001083447
775
86284
P286
S
V
Q
P
Q
V
S
P
R
Q
R
V
Q
R
S
Dog
Lupus familis
XP_849638
440
48261
Cat
Felis silvestris
Mouse
Mus musculus
Q60760
621
70566
N132
P
G
E
N
T
R
G
N
G
K
R
K
I
W
R
Rat
Rattus norvegicus
P0CE43
599
67864
P108
S
V
A
P
S
S
L
P
P
P
P
S
Q
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506127
625
71314
R135
S
L
Q
Q
V
S
P
R
Q
K
V
Q
R
S
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCV1
653
72662
M105
Y
H
F
H
P
P
P
M
P
S
I
I
T
E
D
Zebra Danio
Brachydanio rerio
Q6PFT9
646
70983
P99
S
V
P
V
A
P
A
P
S
K
P
Q
S
N
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34400
779
87484
T213
P
A
L
S
Y
H
Q
T
P
Q
Q
P
Q
L
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
74.7
59.2
N.A.
67.3
68.6
N.A.
83.5
N.A.
22.3
22.7
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
100
100
75.8
64.3
N.A.
74
75.4
N.A.
88.8
N.A.
37.9
38.3
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
100
93.3
0
0
N.A.
6.6
6.6
N.A.
6.6
N.A.
13.3
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
20
0
N.A.
46.6
13.3
N.A.
26.6
N.A.
20
13.3
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% G
% His:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
10
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
30
0
10
0
0
0
% K
% Leu:
0
10
10
0
0
0
10
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% N
% Pro:
20
0
10
20
30
20
20
30
50
10
20
10
0
10
10
% P
% Gln:
0
0
20
30
10
20
10
0
10
20
30
20
30
20
10
% Q
% Arg:
20
0
0
0
0
10
0
10
10
20
20
20
10
10
30
% R
% Ser:
40
20
0
10
10
20
10
20
10
10
0
10
10
10
10
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
0
% T
% Val:
0
30
10
10
10
10
20
0
0
0
10
10
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _